Speakers - WNSC 2024

Abstract

Objective: To study the effect of heated and humidified air sources on bronchopulmonary dysplasia in extremely preterm infants during resuscitation at birth.

Methods: A retrospective analysis was performed on the clinical data of extremely preterm infants admitted to the Department of Neonatology, Shenzhen Maternity and Child Healthcare Hospital. According to the time of resuscitation with a heating and humidification air source, the infants were divided into a non-heating and humidification group and a heating and humidification group. Multivariate Logistic regression analysis was used to analyze the effect of heating and humidification air source resuscitation at birth on bronchopulmonary dysplasia in extremely preterm infants.

Results: A total of 226 extremely preterm infants were enrolled. The incidence rates of BPD in the non-warming and warming groups were 36.59%(45/123) and 22.33%(23/103), respectively. Multivariate Logistic regression analysis showed that compared with the non-heating and humidity group, the risk of BPD in the heating and humidity group was significantly reduced, and the OR value was 0.483(95%CI 0.254, 0.917).

Conclusions: The use of heated and humidified air during resuscitation after birth can reduce the risk of bronchopulmonary dysplasia in extremely preterm infants.

Keywords: Extremely preterm infants, Airway management, Warming, humidification, Bronchopulmonary dysplasia